Seminars in Arthroplasty
Volume 21, Issue 1 , Pages 19-23 , March 2010

Metal-on-Metal Total Hip Arthroplasty Adverse Local Tissue Reaction

  • Charles A. Engh Jr, MD

      Affiliations

    • Anderson Orthopaedic Research Institute, Alexandria, VA, USA
    • Inova Center for Joint Replacement at Mount Vernon Hospital, Alexandria, VA, USA
    • ,
  • Henry Ho, MSc

      Affiliations

    • Anderson Orthopaedic Research Institute, Alexandria, VA, USA
    • ,
  • Charles A. Engh, MD

      Affiliations

    • Anderson Orthopaedic Research Institute, Alexandria, VA, USA
    • Inova Center for Joint Replacement at Mount Vernon Hospital, Alexandria, VA, USA
    • Corresponding Author InformationAddress reprint requests to Charles A. Engh, MD, Anderson Orthopaedic Research Institute P.O. Box 70882501, 2501 Parker's Lane, Suite 200, Alexandria, VA 22306
    • ,
  • William G. Hamilton, MD

      Affiliations

    • Anderson Orthopaedic Research Institute, Alexandria, VA, USA
    • Inova Center for Joint Replacement at Mount Vernon Hospital, Alexandria, VA, USA
    • ,
  • Kevin B. Fricka, MD

      Affiliations

    • Anderson Orthopaedic Research Institute, Alexandria, VA, USA
    • Inova Center for Joint Replacement at Mount Vernon Hospital, Alexandria, VA, USA

References 

  1. Bozic KJ, Kurtz SM, Lau E, et al. The epidemiology of total hip arthroplasty bearing usage in the United States. J Arthroplasty. 2009;24:e44
  2. Huo MH, Gilbert NF. What's new in hip arthroplasty. J Bone Joint Surg Am. 2005;87:2133–2146
  3. Dowson D, Hardaker C, Flett M, et al. A hip joint simulator study of the performance of metal-on-metal joints: Part II: Design. J Arthroplasty. 2004;19(8 suppl 3):124–130
  4. Rieker CB, Schön R, Köttig P. Development and validation of a second-generation metal-on-metal bearing: Laboratory studies and analysis of retrievals. J Arthroplasty. 2004;19(8 suppl 3):5–11
  5. Campbell P, Shimmin A, Walter L, et al. Metal sensitivity as a cause of groin pain in metal-on-metal hip resurfacing. J Arthroplasty. 2008;23:1080–1085
  6. Davies AP, Willert HG, Campbell PA, et al. An unusual lymphocytic perivascular infiltration in tissues around contemporary metal-on-metal joint replacements. J Bone Joint Surg Am. 2005;87:18–27
  7. Hallab N, Merritt K, Jacobs JJ. Metal sensitivity in patients with orthopaedic implants. J Bone Joint Surg Am. 2001;83:428–436
  8. Jacobs JJ, Hallab NJ. Loosening and osteolysis associated with metal-on-metal bearings: A local effect of metal hypersensitivity?. J Bone Joint Surg Am. 2006;88:1171–1172
  9. Mikhael MM, Hanssen AD, Sierra RJ. Failure of metal-on-metal total hip arthroplasty mimicking hip infection (A report of two cases). J Bone Joint Surg Am. 2009;91:443–446
  10. Willert HG, Buchhorn GH, Fayyazi A, et al. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints (A clinical and histomorphological study). J Bone Joint Surg Am. 2005;87:28–36

 Investigation performed at the Anderson Orthopaedic Research Institute, Alexandria, VA.

 Financial support for this work was provided by general research funding from Inova Health System and by a cooperative agreement that was awarded and administered by the US. Army Medical Research and Materiel Command (USAMRMC), and the Telemedicine and Advanced Technology Research Center (TATRC), under Contract Number W81XWH-05-2-0079.

PII: S1045-4527(09)00088-1

doi: 10.1053/j.sart.2009.12.005

Seminars in Arthroplasty
Volume 21, Issue 1 , Pages 19-23 , March 2010

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