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Volume 21, Issue 1, Pages 19-23 (March 2010)


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Metal-on-Metal Total Hip Arthroplasty Adverse Local Tissue Reaction

Charles A. Engh Jr, MD, Henry Ho, MSc, Charles A. Engh, MDCorresponding Author Informationemail address, William G. Hamilton, MD, Kevin B. Fricka, MD

Metal-on-metal (MOM) bearings with large head diameter are commonly used for total hip arthroplasty (THA). They provide low wear and a reduced risk of dislocation. Since 2001, we have done 1327 primary THAs using this bearing surface. Using revision as an endpoint, survivorship is 94% at 8 years. Of the 17 revisions (1.3%), none have been for dislocation. Five patients (0.3%) have shown evidence of a local reaction to the MOM bearing which contributed to their failure and ultimate revision. All 5 presented with elevated inflammatory indexes and had a purulent-appearing joint effusion at revision. Two showed a necrotic periarticular tissue mass (pseudotumor). The presumed diagnosis of infection and the delay in diagnosis of reaction to the MOM with pathology complicated management.

 Anderson Orthopaedic Research Institute, Alexandria, VA, USA

 Inova Center for Joint Replacement at Mount Vernon Hospital, Alexandria, VA, USA

Corresponding Author InformationAddress reprint requests to Charles A. Engh, MD, Anderson Orthopaedic Research Institute P.O. Box 70882501, 2501 Parker's Lane, Suite 200, Alexandria, VA 22306

 Investigation performed at the Anderson Orthopaedic Research Institute, Alexandria, VA.

 Financial support for this work was provided by general research funding from Inova Health System and by a cooperative agreement that was awarded and administered by the US. Army Medical Research and Materiel Command (USAMRMC), and the Telemedicine and Advanced Technology Research Center (TATRC), under Contract Number W81XWH-05-2-0079.

PII: S1045-4527(09)00088-1

doi:10.1053/j.sart.2009.12.005


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