Seminars in Arthroplasty
Volume 20, Issue 4 , Pages 210-216 , December 2009

Pathophysiology of Venous Thromboembolic Disease

References 

  1. Gilmore R, Doyle M, Holden F, et al. Activated protein C resistance, factor V Leiden and assessment of thrombotic risk. Ir Med J. 2008;101:256–257
  2. Morris CD, Creevy WS, Einhorn TA. Pulmonary distress and thromboembolic conditions affecting orthopaedic practice, Chapter 12. In:  Buckwalter JA,  Einhorn TA,  Simon SR editor. Orthopaedic Basic Science: Biology and the Biomechanics of the Musculoskeletal System. 2nd ed.. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2000;
  3. Turpie AG, Chin BS, Lip GY. Venous thromboembolism: Pathophysiology, clinical features, and prevention. BMJ. 2002;325:887–890
  4. Kroegel C, Reissig A. Principle mechanisms underlying venous thromboembolism: Epidemiology, risk factors, pathophysiology and pathogenesis. Respiration. 2003;70:7–30
  5. Dutta TK, Venugopal V. Venous thromboembolism: The intricacies. J Postgrad Med. 2009;55:55–64
  6. Haake DA, Berkman SA. Venous thromboembolic disease after hip surgery (Risk factors, prophylaxis, and diagnosis). Clin Orthop Relat Res. 1989;242:212–231
  7. Ferrari E, Baudouy M, Cerboni P, et al. Clinical epidemiology of venous thromboembolic disease: Results of a French multicentre registry. Eur Heart J. 1997;18:685–691
  8. Trujillo-Santos AJ, Jimenez-Puente A, Perea-Milla E. Association between long travel and venous thromboembolic disease: A systemic review and meta-analysis of case-control studies. Ann Hematol. 2008;87:79–86
  9. Behranwala KA, Williamson RC. Cancer-associated venous thrombosis in the surgical setting. Ann Surg. 2009;249:366–375
  10. Tomasson G, Monach PA, Merkel PA. Thromboembolic disease in vasculitis. Curr Opin Rheumatol. 2009;21:41–46
  11. Keenan CR, White RH. The effects of race/ethnicity and sex on the risk of venous thromboembolism. Curr Opin Pulm Med. 2007;13:377–383
  12. Kim V, Spandorfer J. Epidemiology of venous thromboembolic disease. Emer Med Clin North Am. 2001;19:839–859
  13. Solymoss S. Risk factors for thromboembolism: Pathophysiology and detection. CMAJ. 2000;163:991–994
  14. Wattanakit K, Cushman M, Stehman-Breen C, et al. Chronic kidney disease increases risk for venous thromboembolism. J Am Soc Nephrol. 2008;19:135–140
  15. Gonsalves A, Carrier M, Wells PS, et al. Incidence of symptomatic venous thromboembolism following hematopoietic stem cell transplantation. J Thromb Haemost. 2008;6:1468–1473
  16. Menajovsky LB. Heparin-induced thrombocytopenia: Clinical manifestations and management strategies. Am J Med. 2005;118(suppl 8):21S–30S
  17. Stein PD, Goldman J, Matta F, et al. Diabetes mellitus and risk of venous thromboembolism. Am J Med Sci. 2009;337:259–264
  18. Koutroubakis IE. Therapy insight: Vascular complications in patients with inflammatory bowel disease. Nat Clin Pract Gastroenterol Hepatol. 2005;2:266–272
  19. White RH. The epidemiology of venous thromboembolism. Circulation. 2003;107(suppl 1):I-4–I-8
  20. Bottner F, Sculco TP. Nonpharmacologic thromboembolic prophylaxis in total knee arthroplasty. Clin Orthop Relat Res. 2001;392:249–256
  21. Mammen EF. Pathogenesis of venous thrombosis. Chest. 1992;102(suppl):640S–644S
  22. Merli GJ. Pathophysiology of venous thrombosis and the diagnosis of deep vein thrombosis-pulmonary embolism in the elderly. Clin Geriatr Med. 2008;26:203–219
  23. Becattini C, Agnelli G. Pathogenesis of venous thromboembolism. Curr Opin Pulm Med. 2002;8:360–364
  24. Chung I, Lip GY. Platelets and heart failure. Eur Heart J. 2006;27:2623–2631
  25. Westrich GH, Specht LM, Sharrock NE, et al. Venous haemodynamics after total knee arthroplasty: Evaluation of active dorsal to plantar flexion and several mechanical compression devices. J Bone Joint Surg Br. 1998;80:1057–1065
  26. Sharrock NE, Go G, Sculco TP, et al. Changes in circulatory indices of thrombosis and fibrinolysis during total knee arthroplasty performed under tourniquet. J Arthroplasty. 1995;10:523–528
  27. Murray D, Britton R, Bulstrode C. Thromboprophylaxis and death after total hip replacement. J Bone Joint Surg Br. 1996;78:863–870
  28. Planes A, Vochelle N, Fagola M. Total hip replacement and deep vein thrombosis. J Bone Joint Surg Br. 1990;72:9–13
  29. Prins MH, Hirsh J. A comparison of general anaesthesia and regional anaesthesia as a risk factor for deep vein thrombosis following hip surgery: A critical review. Thromb Haemost. 1990;64:497–500
  30. Sharrock NE, Go G, Harpel PC, et al. Thrombogenesis during total hip arthroplasty. Clin Orthop. 1995;319:16–27
  31. Sharrock NE, Go G, Sculco TP, et al. Dose response of intravenous heparin on markers of thrombosis during primary total hip replacement. Anesthesiology. 1999;90:981–987
  32. DiGiovanni CW, Restrepo A, Gonzalez Della Valle AG, et al. The safety and efficacy of intraoperative heparin in total hip arthroplasty. Clin Orthop. 2000;379:178–185
  33. Westrich GH, Menezes A, Sharrock N, et al. Thromboembolic disease prophylaxis in total knee arthroplasty using intraoperative heparin and postoperative pneumatic foot compression. J Arthroplasty. 1999;14:651–656
  34. Westrich GH, Farrel C, Bono JV, et al. The incidence of venous thromboembolism after total hip arthroplasty: A specific hypotensive epidural anaesthesia protocol. J Arthroplasty. 1999;14:456–463
  35. Sochart DH, Hardinge K. The relationship of foot and ankle movements to venous return in the lower limb. J Bone Joint Surg Br. 1999;81:700–704
  36. McNally MA, Cooke EA, Mollan RA. The effect of active movement of the foot on venous blood flow after total hip replacement. J Bone Joint Surg Br. 1997;79:1198–1201
  37. Gibbs NM. Venous thrombosis of the lower limbs with particular reference to bed rest. Br J Surg. 1957;45:209–236
  38. Payling-Wright H, Osborn S, Edmonds D. Effect of postoperative bed rest and early ambulation on the rate of venous blood flow. Lancet. 1951;257:22–25
  39. Alimi YS, Barthelemy P, Juhan C. Venous pump of the calf: A study of venous and muscular pressures. J Vasc Surg. 1994;20:728–735
  40. Barcroft H, Dornhorst AC. Demonstration of the muscle pump in the human leg. J Physiol. 1949;108:39-39
  41. White JV, Katz ML, Cisek P, et al. Venous outflow of the leg: Anatomy and physiologic mechanism of the plantar venous plexus. J Vasc Surg. 1996;24:819–824
  42. Gardner AM, Fox RH. The venous pump of the human foot: Preliminary report. Bristol Med Chir J. 1983;98:109–112
  43. Gardner AM, Fox RH. The venous footpump: Influence on tissue perfusion and prevention of venous thrombosis. Ann Rheum Dis. 1992;51:1173–1178
  44. Vanhoutte PM, Boulanger CM, Mombouli JV. Endothelium-derived relaxing factors and converting enzyme inhibition. Am J Cardiol. 1995;76(suppl E):3–12
  45. Allenby F, Pflug JJ, Boardman L, et al. Effects of external pneumatic compression on fibrinolysis in man. Lancet. 1973;2:1412–1414
  46. Dai G, Tsukurov O, Orkin RW, et al. An in vitro cell culture system to study the influence of external pneumatic compression on endothelial function. J Vasc Surg. 2000;32:977–987
  47. Kessler CM, Hirsch DR, Jacobs H, et al. Intermittent pneumatic compression in chronic venous insufficiency favorably affects fibrinolytic potential and platelet activation. Blood Coagul Fibrinolysis. 1996;7:437–446
  48. Westrich GH, Specht LM, Sharrock NE, et al. Pneumatic compression hemodynamics in total hip arthroplasty. Clin Orthop. 2000;372:180–191
  49. Ay C, Jungbauer LV, Sailer T, et al. High concentrations of soluble P-selectin are associated with risk of venous thromboembolism and the P-selectin Thr715 variant. Clin Chem. 2007;53:1235–1243
  50. White RH, Romano PS, Zhou H, et al. Incidence and time course of thromboembolic outcomes following total hip or knee arthroplasty. Arch Intern Med. 1998;158:1525–1531
  51. Bergqvist D, Benoni G, Bjorgell O, et al. Low-molecular-weight heparin (enoxaparin) as prophylaxis against venous thromboembolism after total hip replacement. N Engl J Med. 1996;335:696–700
  52. Friedman DG. The structure of thrombi. In:  Coleman RW,  Hirsh J,  Marder VJ, et al. editor. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. 2nd ed.. Philadelphia: J B Lippincott; 1987;p. 1123–1135
  53. Krivec B, Voga G, Zuran I, et al. Diagnosis and treatment of shock due to massive pulmonary embolism: Approach with transesophageal echocardiography and intrapulmonary thrombolysis. Chest. 1997;112:1310–1316
  54. Morgenstern E, Korell U, Richter J. Platelets and fibrin strands during clot retraction. Thromb Res. 1984;33:617–623
  55. Sabovic M, Lijnen HR, Keber D, et al. Correlation between progressive adsorption of plasminogen to blood clots and their sensitivity to lysis. Thromb Haemost. 1990;64:450–454
  56. Chan RK, Johns JA, Calafiore P. Clinical implications of the morphological features of central pulmonary artery thromboemboli shown by transoesophageal echocardiography. Br Heart J. 1994;72:58–62
  57. Lin PH, Chen C, Surowiec SM, et al. Evaluation of thrombolysis in a porcine model of chronic deep venous thrombosis: An endovascular model. J Vasc Surg. 2001;33:621–627
  58. O'Shaughnessy AM, Fitzgerald DE. Determining the stage of organisation and natural history of thrombosis using computer analysis. Int Angiol. 2000;19:220–227

PII: S1045-4527(09)00054-6

doi: 10.1053/j.sart.2009.10.002

Seminars in Arthroplasty
Volume 20, Issue 4 , Pages 210-216 , December 2009

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